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That means: * We cant yet predict *who* will respond best * Optimal dosing for MCAS is still unknown * These medications are often used off-label for MCAS * Cost and access remain real barriers That said, the authors strongly emphasize something important: many MCAS patients responded to much lower doses than those typically prescribed for diabetes or obesity, which may improve tolerability and safety

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In studies with rodents, Wegovy and medicines that work like Wegovy caused thyroid tumors, including thyroid cancer